Testosterone Cypionate

Testosterone Cypionate

Testosterone controls libido for both sexes and distinguishes characteristics of a sex from another. The presence of Testosterone hormone can be found in both sexes but it is predominantly a male androgenic hormone. As free Testosterone in the body will persist for only a few hours, the process of esterification is employed for reducing the water solubility of the steroid and increases the fat solubility. Testosterone Cypionate is a well-known ester used with testosterone for it releases a pretty steady level of the parent hormone over the period of roughly 15 to 16 days. In 1935, the world saw the synthesization of Testosterone. Since then the evolution of various forms of Testosterone took place at the hands of pharmaceutical giants like UpJohn, Organon and so many.

Chemical Name: Testosterone Cypionate
Drug Class: Injectable Anabolic Steroid

Testosterone Cypionate Injections Action:

At the administration of this long-lasting form of Testosterone Cypionate, this injectable steroid starts to store in what is known as depot of the body and is released slowly from there over a short period of time. No sooner does the Testosterone Cypionate injections peak within 1 to 2 days than the testosterone is released over the next 12 days unfluctuatingly and tapers off altogether after about 21 days.

Why are Testosterone Cypionate Injections so important?

Testosterone Cypionate Injections are primarily androgenic synthesized with anabolic (muscle building) characteristics. Testosterone promotes the well-being of the health and enhances Libido or sexual desire, energy, immunity power, reduces fat tissues, prevents loss of bone density(Osteoporosis), maintains lean muscle mass or improves cardiovascular activities. Testosterone is responsible for developing male sex organs and maintaining the biological process of secondary sex traits those distinguish between sexes. Don’t confuse Testosterone being direct part of the reproductive system. The secondary sex organs which are enhanced by the influence of Testosterone are moustache, beard, chest, broad shoulders, spike-projected jaw or well-built muscle mass. Testosterone binds together the Androgen Receptors (AR) that helps muscle gain, fat loss, and muscle growth and repair. These mechanisms are activated by the Androgen Receptors (either directly or as dihydrotestosterone-DHT) and the hormonal cascade as well.

Testosterone Cypionate Results:

Testosterone cypionate results in muscle mass building and body strength enhancing in particular during testosterone cypionate cycle. As with testosterone replacement therapy with testosterone cypionate which has a proclivity for estrogen conversion, the muscle mass building resulting from testosterone cypionate injectables is probably to be added by a noticeable level of water retention. Testosterone cypionate, therefore, may not be a better choice for dieting or cutting phases. One may also grow gynecomastia rather quickly with the excess level of estrogen as caused by Testosterone cypionate. Here, one should be careful of growth of any uncomfortable soreness, swelling or lump under the nipple, and if such is found, one should take an ancillary drug such as Proviron and/or Nolvadex along with Testosterone Cypionate, thereby lessening the rare baneful effects of estrogen and turning the steroid much more endurable to follow. Apart from them, anti-aromatase Arimidex might have been popularly a better choice for its strong effectiveness if its price were not so higher. But ancillary drugs like Proviron and Novaldex will be delicately effective choice as well unless one is detected sensitive to estrogen during a Testosterone Cypionate cycle.

Testosterone Cypionate Dosages:

Testosterone cypionate dosages should be between one and two shot in a week albeit the effects of testosterone injections remain active in the body for a longer time – approximately a couple of weeks. The testosterone cypionate dosages should be cycled in such way because this testosterone cypionate cycle will help bodies keep blood levels relatively constant. Some fussy people even choose more than two time administration in a week! That should be necessarily consulted beforehand with a qualified physician to avoid Testosterone cypionate side-effects. Testosterone cypionate dosages, however, should be of 200 mg ml to 800 mg ml every week and experience surprising and superceding Testosterone cypionate results! But beware of exessive use of Testosterone cypionate! Few years back when the price and popularity regarding the high-perfomace of testosterone cypionte was very low, bodybuilders and athletes used to take more than thrice shots! When testosterone cypionate dosages vary between 800 mg and 1000 mg per week, the water retention will come to be the primary gain and mass accumulation will be surprising as well! But this practice is no more in fashion because of the superb and excellent testosterone cypionate results.

What are the possible Side-effects or health hazards of Testosterone Cypionate Injections?

The acuteness of side-effects is dependent mostly upon the duration and the levels of circulating free testosterone as well as its conversion into other hormones along with androgenic and anabolic effects or side-effects that depend on testosterone cypionate dosages. But its remarkable effects is in muscle building effect with higher Testosterone cypionate dosages. Testosterone is the best known mass building anabolic, which is very effective for men if the testosterone cypionate dosages of the drug is between 200 to 2000 mg per week (women who don’t masculine mass building should avoid this compound and consult a physician before taking this compound if required anyway).

Testosterone Cypionate can be seen converting into both Estrogen (via aromatization) and Dihydrotestosterone (DHT). Excessive estrogen can be detrimental and lead to Gynecomastia or breast tissue growth in men and this kind of trouble may be compiled with loss of sex drive, fat gaining and reduced fat breakdown, water retention and testicular shrinkage. The retention of water can aggravate blood pressure affecting blood vessels in due course. But the estrogenic side-effects can be stopped by using a class of drugs which may stop testosterone from converting to estrogen known as ‘aromatization’. The testicular shrinkage can be prevented by using HCG during a testosterone cycle.

Dihydrotestosterone (DHT) can be a potential cause for male pattern baldness and acne as well.

The natural release of the hormones in one’s body may be hindered by excessive supplementing of Testosterone.

Testosterone Cypionate can inter-act with 5-alpha-reductase enzyme and by doing so, the process can convert testosterone to a more androgenic form of the parent hormone called DHT. This DHT can cause prostate leading to renal problems.

Testosterone cypionate helps to gain in strength (1) and alterations of size, shape and appearance of the muscle can be also possible (2). It is to be noted down that the higher dosage of Testosterone Cypionate is used, the better the results. There might be potential side-effects for higher amounts of androgens in the body at its higher usage (3). Studies relating to the usage of 600 mg dosage per week have revealed that this dosage amount produces greater results like loss of fat, growth of muscle mass, lowered HDL cholestorel, and increased size and strength. Testosterone Replacement Therapy helps gaining 15% muscle mass through 20 weeks of usage of 600 mg per week.

Testosterone Cypionate Profile:

Testosterone base + Cypionate Ester
Formula: C27 H40 O3
Molecular Weight: 412.6112
Molecular Weight (Base): 288.429
Molecular Weight (ester): 132.1184
Formula (base): C19 H28 O2
Formula (ester): C8 H14 O2
Melting point (base): 155
Melting point (ester): 98 – 104 C
Manufacturer: Various
Effective dosage (men): 300-2000mg + week
Effective dosage (women): Not recommended
Active life: 15 – 16 days
Detection time: 3 months
Anabolic/Androgenic ratio: 100/100.


1) J Clin Endrocrinol Metab. 1997 Feb; 82(2):407-13
2) Anat Histol Embryol. 2003 Apr;32(2):70-9
3) Heart. 2004 Aug; 90(8):871-6
4) Fertility and Sterility 33. (1980)201-3